Directory
Deb Clopton
Laboratory Coordinator
School of Arts & Sciences
| Degree | Major | Institution | Year |
|---|---|---|---|
| BS | Biology | Creighton University Omaha, NE |
1987 |
Office Hours:
Tues & Thurs: 11 am - 1 pm
Thurs: 1 pm - 3 pm
or by appointment
Fall 2023
Biol 102-000B, 000F, & 000G / Introductory Zoology Lab
Deb Clopton serves as Lab Coordinator on campus. Prior to her arrival at Peru State
College she conducted research as a laboratory technician at Texas A&M University
and University of Nebraska – Lincoln in reproductive physiology and developmental
biology. She has instructed laboratories in General Biology, Zoology, Ornithology,
Prairie Ecology and Physiology.
Ms. Clopton is currently working with Dr. Richard Clopton on the evolution of gregarines in damselflies and cockroaches in an attempt to understand the forces underlying speciation in hyperdiverse parasitic lineages.
- Sargent KM, Clopton DT, Lu N, Pohlmeier WE, Cupp AS. VEGFA splicing: divergent isoforms regulate spermatogonial
stem cell maintenance. Cell Tissue Res. 2016 Jan;363(1):31-45. doi: 10.1007/s00441-015-2297-2. Epub 2015 Nov 9. PMID: 26553653;
PMCID: PMC4703427.
- Bott RC, Clopton DT, Cupp AS. A proposed role for VEGF isoforms in sex-specific vasculature development
in the gonad. Reprod Domest Anim. 2008 Jul;43 Suppl 2(Suppl 2):310-6. doi: 10.1111/j.1439-0531.2008.01179.x. PMID:
18638140; PMCID: PMC2708602.
- Rathbone MJ, Kinder JE, Fike K, Kojima F, Clopton D, Ogle CR, Bunt CR. Recent advances in bovine reproductive endocrinology and physiology
and their impact on drug delivery system design for the control of the estrous cycle
in cattle. Adv Drug Deliv Rev. 2001 Sep 1;50(3):277-320. doi: 10.1016/s0169-409x(01)00156-9. PMID: 11500232.
- Clopton RE, Steele SM, Clopton DT. Environmental Persistence and Infectivity of Oocysts of Two Species of Gregarines,
Blabericola migrator and Blabericola cubensis (Apicomplexa: Eugregarinida: Blabericolidae),
Parasitizing Blaberid Cockroaches (Dictyoptera: Blaberidae). J Parasitol. 2016 Apr;102(2):169-73. doi: 10.1645/15-934. Epub 2016 Jan 15. PMID: 26771541.
- Sargent KM, Lu N, Clopton DT, Pohlmeier WE, Brauer VM, Ferrara N, Silversides DW, Cupp AS. Loss of vascular endothelial
growth factor A (VEGFA) isoforms in granulosa cells using pDmrt-1-Cre or Amhr2-Cre
reduces fertility by arresting follicular development and by reducing litter size
in female mice. PLoS One. 2015 Feb 6;10(2):e0116332. doi: 10.1371/journal.pone.0116332. PMID: 25658474; PMCID:
PMC4320103.
- Kolman JA, Clopton RE, Clopton DT. Effects of Developmental Temperature on Gametocysts and Oocysts of Two Species of
Gregarines Blabericola migrator and Blabericola cubensis (Apicomplexa: Eugregarinida:
Blabericolidae) Parasitizing Blaberid Cockroaches (Dictyoptera: Blaberidae). J Parasitol. 2015 Dec;101(6):651-7. doi: 10.1645/14-673. Epub 2015 Aug 6. PMID: 26248890.
- Bott RC, Clopton DT, Fuller AM, McFee RM, Lu N, McFee RM, Cupp AS. KDR-LacZ-expressing cells are involved
in ovarian and testis-specific vascular development, suggesting a role for VEGFA in
the regulation of this vasculature. Cell Tissue Res. 2010 Oct;342(1):117-30. doi: 10.1007/s00441-010-1038-9. Epub 2010 Sep 17. PMID:
20848132; PMCID: PMC3033580.
- Lu N, Sargent KM, Clopton DT, Pohlmeier WE, Brauer VM, McFee RM, Weber JS, Ferrara N, Silversides DW, Cupp AS.
Loss of vascular endothelial growth factor A (VEGFA) isoforms in the testes of male
mice causes subfertility, reduces sperm numbers, and alters expression of genes that
regulate undifferentiated spermatogonia. Endocrinology. 2013 Dec;154(12):4790-802. doi: 10.1210/en.2013-1363. Epub 2013 Oct 29. PMID: 24169552;
PMCID: PMC3836063.
- Baltes-Breitwisch MM, Artac RA, Bott RC, McFee RM, Kerl JG, Clopton DT, Cupp AS. Neutralization of vascular endothelial growth factor antiangiogenic isoforms
or administration of proangiogenic isoforms stimulates vascular development in the
rat testis. Reproduction. 2010 Aug;140(2):319-29. doi: 10.1530/REP-09-0456. Epub 2010 May 10. PMID: 20457593;
PMCID: PMC3122080.
- 10: Bott RC, McFee RM, Clopton DT, Toombs C, Cupp AS. Vascular endothelial growth factor and kinase domain region receptor
are involved in both seminiferous cord formation and vascular development during testis
morphogenesis in the rat. Biol Reprod. 2006 Jul;75(1):56-67. doi: 10.1095/biolreprod.105.047225. Epub 2006 May 3. PMID:
16672722; PMCID: PMC2366204.
- McFee RM, Artac RA, McFee RM, Clopton DT, Smith RA, Rozell TG, Cupp AS. Inhibition of vascular endothelial growth factor receptor
signal transduction blocks follicle progression but does not necessarily disrupt vascular
development in perinatal rat ovaries. Biol Reprod. 2009 Nov;81(5):966-77. doi: 10.1095/biolreprod.109.078071. Epub 2009 Jul 15. PMID:
19605787; PMCID: PMC2770022.
- Artac RA, McFee RM, Smith RA, Baltes-Breitwisch MM, Clopton DT, Cupp AS. Neutralization of vascular endothelial growth factor antiangiogenic isoforms
is more effective than treatment with proangiogenic isoforms in stimulating vascular
development and follicle progression in the perinatal rat ovary. Biol Reprod. 2009 Nov;81(5):978-88. doi: 10.1095/biolreprod.109.078097. Epub 2009 Jul15. PMID:
19605786; PMCID: PMC2770023.
- Quintal-Franco JA, Kojima FN, Melvin EJ, Lindsey BR, Zanella E, Fike KE, Wehrman ME,
Clopton DT, Kinder JE. Corpus luteum development and function in cattle with episodic release
of luteinizing hormone pulses inhibited in the follicular and early luteal phases
of the estrous cycle. Biol Reprod. 1999 Oct;61(4):921-6. doi: 10.1095/biolreprod61.4.921. PMID: 10491625.
- Steele SM, Clopton DT, Clopton RE. Excystation signals do not isolate gregarine gene pools: experimental
excystation of Blabericola migrator among 11 species of cockroaches. J Parasitol. 2012 Oct;98(5):946-50. doi: 10.1645/GE-3122.1. Epub 2012 Apr 27. PMID: 22540337.
- Fauver JR, Clopton RE, Clopton DT. Protomagalhaensia richardsoni n. sp. (Apicomplexa: Eugregarinida: Blabericolidae):
a new gregarine parasitizing the giant lobster cockroach, Henschoutedenia flexivitta
(Dictyoptera: Blaberidae). J Parasitol. 2013 Oct;99(5):794-802. doi: 10.1645/13-202.1. Epub 2013 May 9. PMID: 23659501.
- Kojima FN, Bergfeld EG, Wehrman ME, Cupp AS, Fike KE, Mariscal-Aguayo DV, Sanchez-Torres T, Garcia-Winder M, Clopton DT, Roberts AJ, Kinder JE. Frequency of luteinizing hormone pulses in cattle influences duration of persistence of dominant ovarian follicles, follicular fluid concentrations of steroids, and activity of insulin-like growth factor binding proteins. Anim Reprod Sci. 2003 Jul 15;77(3-4):187-211. doi: 10.1016/s0378-4320(03)00038-1. PMID: 12695054.